Milrinone for persistent pulmonary hypertension of the newborn
نویسندگان
چکیده
منابع مشابه
Milrinone improves oxygenation in neonates with severe persistent pulmonary hypertension of the newborn.
BACKGROUND Many neonates with severe persistent pulmonary hypertension of the newborn (PPHN) are nonresponders to inhaled nitric oxide (iNO). Milrinone is a promising adjunctive therapy because of its pulmonary vasodilator properties and cardiotropic effects. DESIGN Case series of neonates with severe PPHN (defined as oxygenation index [OI] >20, failure of iNO therapy, and echocardiographic c...
متن کاملPersistent Pulmonary Hypertension of the Newborn
Introduction: Persistent pulmonary hypertension of the newborn (PPHN) was first described by Gersony et al 1 of persistence of the fetal circulation in 1969. It is a clinical syndrome characterized by respiratory distress, hypoxemia, elevated pulmonary vascular resistance and a right to left shunting of venous blood across the foramen ovale and/or ductus arteriosus. The etiology of PPHN is not ...
متن کاملPersistent Pulmonary Hypertension in the Newborn
Persistent pulmonary hypertension of the newborn (PPHN) is characterized by elevated pulmonary vascular resistance resulting in right-to-left shunting of blood and hypoxemia. PPHN is often secondary to parenchymal lung disease (such as meconium aspiration syndrome, pneumonia or respiratory distress syndrome) or lung hypoplasia (with congenital diaphragmatic hernia or oligohydramnios) but can al...
متن کاملPrevalence of Persistent Pulmonary Hypertension of the Newborn and Associated Factors in Term Neonates Born in Southeast of Iran, 2020
Background and purpose: Infants with persistent pulmonary hypertension (PPHN) are readmitted to hospital three times more than other infants or die after discharge. The disease imposes a high cost on families and health systems. In this study, for the first time, the prevalence of PPHN and associated factors were investigated in mature neonates born in southeast of Iran. Materials and methods...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2010
ISSN: 1465-1858
DOI: 10.1002/14651858.cd007802.pub2